[Clinical-physiological aspects of normobaric hypoxic training effects on functional status of patients with neurocirculatory dystonia]. / Kliniko-fiziologicheskie aspekty vliianiia normobaricheskoi gipoksicheskoi trenirovki na funktsional'noe sostoianie bol'nykh neirotsirkuliatornoi distoniei.

Profiles of external respiration and circulation, self-assessment of health, mental performance, sensory functions, and peripheral blood were studied in patients with neurocirculatory dystonia in the course of normobaric hypoxic training. The hypoxic training proved to successfully normalize arterial pressure, eliminate cardiac arrhythmias, and benefit general condition. Substantial strengthening of hypoxic resistance was stated along with an oxygen debt reduction during hypoxia, improvement of sensory coordination and mental performance, and activation of erythropoiesis.

[Methodological aspects and clinicophysiological substantiation of applying the hypoxic therapy]. / Metodologicheskie aspekty i kliniko-fiziologicheskoe obosnovanie primeneniia gipoksiterapii.

The paper gives the methodical and clinicophysiological substantiation of the hypoxic therapy, a new nonmedicamentous method of body sanitation, raising its physiological reserves, prevention of pathological states, treatment and medical rehabilitation of patients based on breathing air with a reduced O2 partial pressure for the purposes. Health damaging and improving effects of hypoxic hypoxia, perspectives of this therapy from the standpoint of prevention and treatment of myocardial ischemia are discussed. Results of the fundamental studies unveiling the mechanisms of ischemic, reperfusion-induced disorders of myocardium and assessing possibilities of their blockage of the hypoxic therapy are considered. On the literary and own evidence, the authors analyse effectiveness, merits and drawbacks of different (mountain/climatic, hypobaric, normobaric) techniques of hypoxic therapy. Informative criteria for determination of hypoxic resistance of the patient with coronary diseases and choice of individual hypoxic regimen are rationalized.

[Changes in cardiac rhythm in humans during breathing compressed air under pressure up to 1.1 MPa (results of the rhythmo-cardiographic study)]. / Izmenenie serdechnogo ritma u cheloveka vo vremia dykhaniia szhatym vozdukhom pod davleniem do 1.1 MPa (rezul'taty ritmo-kardiograficheskogo issledovaniia).

Dynamics of cardiac rhythm has been considered according to rhythmocardiographic characteristics of heart rate under orthostatic test and one-stage step-test in four altitude chamber experiments where air under pressure of 0.4-1.1 MPa is used as a breathing mixture. It is shown that these characteristics linearly depend on the partial nitrogen and oxygen pressure and hyperbaric bradycardia essentially decreases in the final period of isopression due to toxic oxygen effect. Cytochrome C decreases hyperbaric bradycardia. Under hyperbaric conditions the regulation of cardiac rhythm proceeds with altered central vegetative effects provided a direct effect of higher nitrogen and oxygen pressure on the sinusal node cells.

[Rheographic indicators of blood circulation in the brain and limbs during active orthostatic test]. / Dinamika reograficheskikh pokazatelei mozgovogo krovoobrashcheniia i krovoobrashcheniia v konechnostiakh pri aktivnoi ortostaticheskoi probe.

Rheography was used to study brain, leg and forearm circulation in 30 male test subjects during tilt tests. In the head-up position blood circulation in the above body parts decreased due to a reduction of stroke volume. The orthostatic reaction was considered normal, provided that leg blood content decreased and tone increased, cerebral and forearm blood content and tone varied slightly, and rheographic parameters in the stationary states (lying and standing) remained unchanged.